An Extracellular Matrix Overlay Model for Bioluminescence Microscopy to Measure Single-Cell Heterogeneous Responses to Antiandrogens in Prostate Cancer Cells
Prostate cancer Voucher (PCa) displays diverse intra-tumoral traits, impacting its progression and treatment outcomes.This study aimed to refine PCa cell culture conditions for dynamic monitoring of androgen receptor (AR) activity at the single-cell level.We introduced an extracellular matrix-Matrigel (ECM-M) culture model, enhancing cellular track